铜催化1, 4-二炔硼质子化反应制备支链烯基硼化合物

Regioselective synthesis of branched alkenylborons via copper-catalyzed protoborylation of 1,4-diynes

摘要: 本文报道了铜催化1,4-二炔的高区域选择性硼质子化反应用于合成烯基硼类化合物。该反应对于各种（杂）芳基和烷基取代的末端1,4-二炔底物均能以较高的产率和区域选择性生成相应的产物，反应产物容易发生衍生化反应转化为多种有用的产物。

Abstract: A copper-catalyzed highly regioselective protoborylation of 1,4-diynes for the synthesis of alkenylboramide compounds was reported. Various (hetero)aryl and alkyl substituted terminal 1,4-diynes afforded the corresponding products in high yields and regioselectivities. The utility of alkenyl-B(dan) products was proven by their convenient derivatizations.